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14 December 2017
 
Ali Reza Mohajel Nayebi ,Ph.D


Title:Professor of  Pharmacology
Department:Pharmacology
Office Phone:+98(41)33372252
Fax:+98 (41)33344798
E-mail:nayebia@tbzmed.ac.ir
nayebia@yahoo.com

Academic qualifications:
  • PharmD: 1992, in Pharmacy, from Tehran Medical Sciences University, Tehran, Iran
  • PhD: 1998, in Pharmacology, from Shaheed Beheshti University of Medical Sciences, Tehran, Iran
Positions held:
  • 1998-2002: Assistant Professor of  Pharmacology
  • 2002- 2010: Associate professor of Pharmacology
  • 2010-present: Professor of Pharmacology
Research experiences:
  • Behavioural Study of Pain
  • Tolerance to Anlgesic Effect of Opioids
  • Drugs Dependency
  • Parkinson’s Disease
  • Alzheimer Disease
  • Skin Cancer
Current Research:
Effect of Steroidal Hormones in Parkinson’s Disease and Alzheimer

Teaching experiences:

  • Pharmacology for Phramacy, Medical an Dentistry Pharm.D Students, Pharmacology for Ph.D Students of Pharmacology, Biochemistary and Dentistary. Pharmacology for Nursing, Midwifery and Health Care Students. Drug Information for Pharmacy Students
  • Supervising of Pharm D. and Ph.D  Students
Administrative experiences:
  • Deputy Dean, Research and Education
  • Deputy Dean, Education
  • Member of Toxicological board
  • Head of Department
  • Director of Shahid Motahary Pharmacy
  • Editorial Board of Journal of ‘Pharmaceutical Sciences’
  • Editorial Board of Journal of ‘Advanced Pharmaceutical Bulletin’
Professional memberships:
  • Iranian Association of Physio-Pharmacology
  • Iranian Association of Pharmaceutical Scientists
  Books


National Formulary of Iran (NFI)


Techniques in Laboratory Animals Practice

Experimental Models of Parkinson’s Disease

  Publication

1.     Javad Mahmoudi , Alireza Mohajjel Nayebi , Siyamak Reyhani-Rad , Morteza Samini . Flouxetine Improves the Effect of Levodopa on 6-Hydroxy Dopamine-Induced Motor Impairments in Rats. Advanced Pharmaceutical Bulletin 2012, 2: 149-155

2.      Hamdolah Sharifi, Alireza Mohajjel Nayebi, Safar Farajnia.The Effect of Chronic Administration of Buspirone on 6-Hydroxydopamine-Induced Catalepsy in Rats. Advanced Pharmaceutical Bulletin 2012, 2:127-131

3.     Haddadi R.*1,3, Tamaddonfard E.2, Eyvari-brooshqalan Sh.2, Mohajjel Nayebi A. Study of curcumin mechanism by using yawning induced by physostigmine and pilocarpine in rats. Pharmaceutical Sciences, 2012, 17: 275- 282.

4.      Mohajjel Nayebi A, Sharifi H, Ramadzani M, Rezazadeh H. Effect of acute and chronic administration of carbamazepine on cis-platin-induced hyperalgesia in rats. Jundishapur Nat Pharm Prod 2012: 6: 27-30.

5.      Mahmoudi J, Mohajjel Nayebi A, Samini M, Reyhani-Rad S, Babapour V. Buspirone improves the anti-cataleptic effect of levodopa in 6-hydroxydopamine-lesioned rats. Pharmacological Reports 2011, 63:908-914.

6.      Mahmoudi J, Mohajjel Nayebi A, Samini M, Reyhani-Rad S, Babapour V. 5-HT1A receptor activation improves anti-cataleptic effects of levodopa in 6-hydroxydopamine-lesioned rats. DARU 2011, 19:338-343.

7.      Rezai-Basiri M, Ghazi-Khansari M, Faghih M, Sadeghi M, Lotfalizadeh N, Eghbal M, Mohajjel Nayebi A, Arshad Zadeh M. Screening of Morphine & Codeine in Urine of Opioid Abusers by Rapid and TLC Analysis. Eur J Gen Med 2010, 7:192-196.

8.      Nayebi AM. Hypothesis: A promising effect of 5-HT1A receptor agonists in alleviating motor symptoms of Parkinson's disease. Afr J Pharm Pharmacol 2010, 4:289-290.

9.     Malek A, Ghezel M, Ahmadiasl N, Dastgiri S, Jassur MD, Nayebi AM. Infulence of moon phases on serum level of sodium and lithium: a quasi-experimental study on rabbits. Biol Rhytm Res 2010, 1:1-8.

10.  Charkhpour M, Mohajjel Nayebi A, Doustar Y, Hassanzadeh K. 8-OH-DPAT prevents morphine-induced apoptosis in rat's dorsal raphe nucleus: a possible mechanism for attenuating morphine tolerance. Anesthesia and Analgesia. 2010, accepted for publishing

11.  Mohajjel Nayebi A, Reyhani Rad S, Mahmoodi J, Samini M. Effect of fluoxetine on motor disorders induced by intranigral injection of 6-hydroxydopamine in rats. Pharmaceutical Sciences, 2010, 16:47-56.

12.  Alireza Mohajjel Nayebi, Hassan Rezazadeh, Mostafa Nourafkan. Buspirone attenuates tolerance to analgesic eefect of morphine in mice with skin cancer. Pak J Pharm Sci, 2010, 23: 201-206.

13.  Mohajjel Nayebi A, Sheidaei H. Buspiron improves haloperidol-induced Parkinson disease in mice through 5-HT1A  receptors. Daru, 2010, 18:41-45.

14.  Alireza M. Nayebi, Siyamak Reyhani Rad, Mehdi Saberian, Saeid Azimzadeh, Morteza Samini. Buspirone improves 6-hydroxydopamine-induced catalepsy through stimulation of nigral 5-HT1A receptors in rat. Pharmacological Reports, 2010, 62:62-68.

15.  Hashemi A, Nayebi A, Sadegi MR, Faramarzi A, Delazar A, Rezazadeh H. Study of the methanolic extract of Peganum seeds on convulsion induced by strychnine in swiss mice. Pharmaceutical Sciences, 2009, 15:257-262.

16.  Mohajjel Nayebi Alireza, Barzegar Jalali Mohammad, Saeed Pourmohammad. Study of analgesic effect of naproxen solid dispersions in crosspovidone and Elaeagnus Angustifolia fruit powder  by using formalin test. Pharmaceutical Sciences, 2009, 15:125-132

17.  Mohajjel Nayebi Alireza, Rezazadeh Hassan, Parsa Yousef. Effect of fluoxetine on tolerance to analgesic effect of morphine in mice with skin cancer. Pharmacological Reports, 2009, 61:453-458

18.  Mohajjel Nayebi A, Nazemiyeh H. Omidbakhsh R, Çobanoglu S. Analgesic effect of the methanol extract of Erica arborea (L.) in mice using formalin test. Daru, 2008, 16:229-232.

19.          Mohajjel Nayebi Alireza, Asadi Masoud. Effect of buspirone on morphine withdrawal syndrome  in mice . Pharmaceutical Sciences, 2009, 14:229-235

 20.  Rezazadeh Hasssan, Delazar Abbas, Mohajjel Nayebi Alireza, Abdulla Mohamaed. Inhibitory effect of chrosophora tinctoria extract (methanol) on ferric nitriloacetate-induced oxidative stress in rat kidney tissue.  Cell Biol Toxicol (2008)24 (suppl 1):S1-S130

21.  Mohajjel Nayebi Alireza, Rezazadeh Hassan, Parsa Yousef, Abdulla Mohamed. Effect of fluoxetine on tolerance to analgesic effect of morphine in mice with skin cancer. Cell Biol Toxicol (2008)24 (suppl 1):S1-S130.

22.  Mohajjel Nayebi A , Rajabli B, Nazemiyeh H. Analgesic effect of methanolic extract of Erica Arborea in mice by using hot plate test. Pharmaceutical Sciences, Summer (2008) 45-51.

23.  Nayebi AR, Rezazadeh H. Effect of testosterone on morphine withdrawal syndrome in rats.Asian J Androl. 2008 Sep;10(5):765-9.

 24.  Charkhpour M , Mohajjel Nayebi A, Shiva A.Evaluation the antinociception effect of chronic use of buspirone and effect of that in tolerance to morphine analgesia in mice. Pharmaceutical Sciences, Winter (2007) 35-42.

 25.  Rezazadeh H, Nazemiyeh H, Delazar A, Mohajjel Nayebi A, Mehdipour S. The Inhibitory Effects of Chrozophora tinctoria Extract on Benzoyl peroxide-promoted skin carcinogenesis. Pharmaceutical Sciences, Autumn (2006) 39-42.

26.    Barzegar-Jalali Mohammad, Mohajjel Nayebi Alireza, Valizadeh Hadi, Hanaee Jalal, Barzegar-Jalali Azim, Adibkia Khosro, Anoush Mahdieh, Sistanizad Mohammad. Evaluation of in vitro-in vivo correlation and anticonvulsive effect of carbamazepine after cogrinding with microcrystalline cellulose. J Pharm Pharm Sci. 2006;9(3):307-16.

27.  Nayebi AR, Charkhpour M. Role of 5-HT(1A) and 5-HT(2) receptors of dorsal and median raphe nucleus in tolerance to morphine analgesia in rats. Pharmacol Biochem Behav. 2006 83:203-207.

28.  Charkhpour M, Nayebi AM. Evaluation of  the role of 5-HT1A receptors in dorsal and median raphe nuclei on the morphine withdrawal syndrome in rat. Eur Neuropsychopharmacology 2006; 16:S510-S511.

29.  Charkhpour M, Nayebi AM. Evaluaation of the role of 5-HT1A receptors in dorsal and median raphe nuclei on the morphine withdrawal syndrome in rat. Pharmaceutical Sciences, Autumn(2005), 73-80.

30.  Maleki N, Nayebi AM, Garjani A. Effect of central and peripheral depletion of serotonergic system on carrageenan-induced paw oedema. Int. Immunopharmacol. 2005; 5:1723-1730.

31.  Rezazadeh H, Nayebi AR, Garjani A, Sheikhulislami A, Babaei H. Evidence that iron overload plus croton oil induce skin tumours in mice. Hum. Exp. Toxicol. 2005; 24:409-413.

32.  Maleki N, Nayebi ARM, Garjani A., Fakhrjou A Effect of central and peripheral depletion of serotonergic system on carrageenan-induced paw oedema. Pharmaceutical Sciences, Spring(2005), 75-84.

33.  Charkhpour M, Nayebi ARM. Effect of serotonergic nervs lesion in dorsal and median raphe nuclei on the development of tolerance to morphine analgesia in male rats. Pharmaceutical Sciences, Summer(2005), 17-23.

34.  Nayebi ARM, Rezazadeh H. Involvement of the serotoninergic mechanism in analgesia by castration and flutamide, a testosterone antagonist, in the rat formalin test. Pharmacol. Biochem. Behav. 2004; 77:9-14.

35.  Babaei H, Nayebi ARM, Rezazadeh H, Abdulla M. Inhibitory effect of tannic acid on iron-dextran-agumented and 7,12-dimethylbenz(a)anthracene-initiated skin carcinogenesis. The Journal of Trace Elements in Experimental Medicine 2004; 17:21-29.

36.  Fattahi E, Motamedi R, Nayebi ARM, Rezazadeh H, Shakir A. Triple therapy using two dosages of metronidazole along with amoxicillin and omeprazole to eradicate Helicobacter pylori infection: a randomized, open study. Indian J. Gastroenterol. 2004; 23:154.

37.  Nayebi ARM, Nagedi F. The effect of fluoxetine on tolerance to analgesic effect of morphine in male rats. Pharmaceutical Sciences, Journal of Faculty of Pharmacy 2004; spring-summer 129-137(Persian)

38.  Nayebi AM, Pourfarhad D. The role of spinal serotonergic system in morphine withdrawal syndrome in the rat. Iranian Journal of Pharmaceutical Research 2004; suppl. 3:46.

39.  Nayebi ARM, Hassanpour M, Rezazadeh H. Effect of chronic and acute administration of fluoxetine and its additive effect woth morphine on the behavioural response in the formalin test in rats. J. Pharm. Pharmacol. 2001; 53:219-225.

40.  Rezazadeh H, Nayebi AR, Athar M. Role of iron-dextran on 7,12-dimethylbenz(a)anthracene-initiated and croton oil-promoted cutaneous tumorigenesis in normal and pregnant mice. Hum. Exp. Toxicol. 2001; 20:471-476.

41.  Nayebi AR, H Babei, Samieh K. The effect of chronic and acute administration of fluoxetine on acute pain and possible role of opioidergic system using hot plate test.Pharmaceutical Sciences, 2001; 1:85-94.

 42.  Babaei H, Nyaebi ARM. Studying possible mechanisms of acute vasorelaxant effect of 17-B estradiol. Pharmaceutical Sciences, 2001; 1: 1-8.

 43.  Nayebia ARM, Ahmadiani A. (2000) Possible role of opioidergic system in serotonin induced analgesia in the formalin test. Pharmaceutical Sciences, 2000; 3:79-84.

 44.  Nayebi AR, Ahmadiani A. Involvement of the spinal serotonergic system in analgesia produced by castration. Pharmacol. Biochem. Behav. 1999; 64:467-471.

  Presentations

1.      Mohajjel Nayebi A. Role of 5-HT1A receptor in tolerance to analgesic effect of morphine in mice using Hot-Plate test. The 11th Iranian Pharmaceutical Sciences Conference  2008 (IPSC2008). Kerman-Iran

2.      Mohajjel Nayebi A, Rezazadeh H. Effect of buspirone on tolerance to analgesic effect of morphine in mice with skin cancer. The 11th Iranian Pharmaceutical Sciences Conference  2008 (IPSC2008). Kerman-Iran

3.        Mahmoudi J, Reyhani Rad S., Mohajjel Nayebi A. Effect of verapamil on tramadol toxic dose related seizures in rat.  12th Iranian Pharmaceutical Science Congress (IPSC2010), 2-5 August 2010,  Zanjan, Iran

 4.      Mohajjel Nayebi A, Mahmoudi J, Reyhani Rad S. The effect of buspirone on improving levodopa effectiveness in hemiparkisonian rats. 12th Iranian Pharmaceutical Science Congress (IPSC2010), 2-5 August 2010,  Zanjan, Iran

 5.        Nayebi AM , Saberian M, Azimzadeh S, Rezazadeh H.Effect of Buspirone on 6-OH-Dopamine-Induced  Catalepsy in Rat. 28th Annual Conference of Society of Toxicology (STOX), and International Symposium on “Monitoring and Modulating Global Resources of Environmental and Food Contaminants: Nature versus Chemicals” October 16-18, 2008, Ludhiana-India.

6.        Mohajjel Nayebi Alireza, Rezazadeh Hassan, Parsa Yousef, Abdulla Mohamed. Effect of fluoxetine on tolerance to analgesic effect of morphine in mice with skin cancer. ISTERH-NTES-HTES' 07 Conference, October 21 to 26, 2007, Crete-Greece.

7.        Rezazadeh Hasssan, Delazar Abbas, Mohajjel Nayebi Alireza, Abdulla Mohamaed. Inhibitory effect of Chrozophora tinctora extract (methanol) on ferric nitrilotriacetate induced oxidative stress in rat kidney tissue. ISTERH-NTES-HTES' 07 Conference,October 21 to 26, 2007, Crete-Greece.

8.         Maleki N, Nayebi ARM, Garjani A. The effect of central serotonergic and peripheral depletion of serotonergic system on carrageenan-induced paw oedema. 17th Iranian congress of physiology and pharmacology, Kerman-Iran, 1-4 October 2005

9.      Nayebi ARM. Seiyede Goganee M, Anoosh M. Study of the effect of testosterone on morphine withdrawal syndrom in rats. 17th Iranian congress of physiology and pharmacology, Kerman-Iran, 1-4 October 2005

10.  Nayebi ARM. Charkhpour M. Role of 5-HT1A and 5-HT2 receptors of DRN on morphine withdrawal syndrom in male rats. 17th Iranian congress of physiology and pharmacology, Kerman-Iran, 1-4 October 2005

11.  Charkhpour M, Nayebi AM. Effect of serotonergic nervs lesion in dorsal and median raphe nucleus on the development of tolerance to morphine antinociception in the rat. 9th seminar of pharmaceutical sciences Tabriz, Aug 23-26, 2004

12.  Sistaneezad, M., Nayebi A.M., Barzgar Jalali, M. Investigation of plasma concentration of soild dispersion of carbamazepine and its powder in rabbits. 9th seminar of pharmaceutical sciences Tabriz, Aug 23-26, 2004

 13.  Nayebi, A.M., Argawanian, N. Role of central serotoninergic system in tolerance to analgesic effect of morphine using hot plate test. 9th seminar of pharmaceutical sciences Tabriz, Aug 23-26, 2004

 14.  Anoosh, M., Nayebi, A.M., Barzgar Jalali, M. Investigation on antiseizure effects of carbamazepine solid dispersion in mice. 9th seminar of pharmaceutical sciences Tabriz, Aug 23-26, 2004

 15.  Nayebi ARM, Bargozin R. Effect of Fluoxetine on Antinociceptive effect of Flutamide in Male Rats. 9th Asian and Pacific Congress of Clinical Biochemistry, 16thNov. 2001, Newdelhi

 16.  Nayebi ARM. Antinociceptive effect of fluoxetine in the formalin test in rats. 8th Southeast Asia-Western Pacific Regional Meeting of Pharmacologists, Taipei,November 1-5, 1999

 17.  Ahmadiani A, Nayebi ARM, Haeri A, Haydarbaigi A. Role of cerebral and spinal serotonergic system in pain control, a study by microdialysis technique. 14th Iranian Congress of Physiology and Pharmacology, 16-20 May, 1999

 18.  Rezazadeh H, Gandiha H, Garjani A, Nayebi ARM, Babaei H, Athar M. Iron overload augments coroton oil-mediated tumor production in mouse skin. 14 th Iranian Congress of Physiology and Pharmacology, 16-20 may, 1999

 19.  Nayebi ARM. Site of action of 5-hydroxytryptamine in modulating formalin induced chronic pain. XIII International Congress of Physiological Sciences, St.Petersburg, Russia, June 30-July 5, 1997

 20.  Nayebi ARM. Spinal microdialysis in male rats shows that testosterone receptor controls 5-HT release, II Congress of the European Federation of IASP Chapters, 24-27 September 1997

 21.  Nayebi ARM. Study of serotonergic system involvement in gonadectomy induced analgesia by using spinal microdialysis. 3th Iranian Congress of Physiology and Pharmacology, Isphahan 1997

 22.  Nayebi ARM. Serotonergic system involvement in gonadectomy induced analgesia of male rats. 1ST Iranian Congress of Neuroscience Shaheed Beheshti University of Medical Sciences and Health Services, November 27-29, 1996

 23.  Nayebi ARM. Site of action of 5-hydroxytryptamine in modulating formalin induced chronic pain, 1ST Iranian Congress of Neuroscience Shaheed Beheshti University of Medical Sciences and Health Services, November 27-29, 1996

 Grants

Effect of fluoxetine on castration-induced analgesia in male rats using formalin test.

The Effect of Fluoxetine on Tolerance to Analgesic Effect of Morphine in Male Rats.

The effect of testosterone on morphine withdrawal syndrom in rats.

The effect of spinal serotonergic system on morphine withdrawal syndrom in male rats.

Evaluation of effect of DRN serotonergic neurons lesion on 5-HT and 5-HIAA levels alterations in rat hippocampus after development of  morphine tolerance using cerebral microdialysis study.

■ Study and Revision of educational roles of thesis, Tabbriz university of medical sciences. 

The role of serotonergic system of the DRN and MRN on tolerance to analgesic effect of morphine in male rat.

■ Study on the analgesic effect of naproxen solid dispersions in crosspovidone and Elaeagnus angustifolia fruit powder.     

Effect of buspirone on morphine  withdrawal syndrom in mice.

Effect of buspirone on tolerance to morphine analgesic effect in mice.

Effect of buspirone on MPTP and Haloperidol-induced motor dysfunction in mice.

Role of 5-HT1A receptors in 6-OH dopamine-induced motor deficit in rats and assessment of dopamine level in striatum by using microdialysis technique.                       
Posted by   Farnam Norouzi