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22 September 2017
 
Mohammad Ali.Eghbal ,Ph.D

Title:Associate Professor of Pharmacology & Toxicology
Department:Pharmacology & Toxicology
Office Phone:+98(41)33372250-51
Fax:+98(41)33344798
E-mail:m.eghbal@utoronto.ca

Educational Background:
MSc: 1999 in Toxicology, from University of Toronto, Toronto, CANADA
PharmD: 1989, from Tabriz University of Medical Sciences, Tabriz, IRAN
PhD: 2004, in Pharmacology and Toxicology, from University of Toronto, Toronto, CANADA

Positions held:
  • 1990-1996: Instructor in pharmacology
  • Teaching Assistant. September 2002- April 2003. Faculty of Pharmacy, University of Toronto, Toronto, Canada. Pharmaceutics Laboratory. PHM 224Y.
  • September 1997- April 2002. Faculty of Pharmacy, University of Toronto, Toronto, Canada. Medicinal Chemistry PHM 222Y Channels, pumps and transporters section.
  • January –April 1999. Faculty of Pharmacy, University of Toronto, Toronto, Canada. Metabolic Biochemistry PHM 226S. Neurons and Glial Cells section. 
  • 2004-present: Assistant professor of pharmacology
Research experiences:
Pharmacology of Neuromuscular Junctions, Hepatitis induced by xenobiotics and protective effects of chemicals and natural products, Drug metabolism, Biological studies on organotypic hippocampal slice cultures

Current Research:
Hepatitis induced by xenobiotics and protective effects of chemicals and natural products, Drug metabolism

Teaching experiences:
Pharmacology, Molecular toxicology

Administrative experiences:
July 4005- Head, Department of Pharmacology and Toxicology, Faculty of Pharmacy, Tabriz University of Medical Sciences
  Publications

1. Mohammad A. Eghbal, Shahrzad Tafazoli, Peter Pennefather and Peter J. O’Brien. Peroxidase catalysed formation of cytotoxic prooxidant phenothiazine free radicals at physiological pH Chem Biol Interact. 2004 Dec 30;151(1):43-51.

2.  Eghbal MA, Pennefather PS, O'Brien PJ. H2S cytotoxicity mechanism involves reactive oxygen species formation and mitochondrial depolarisation. Toxicology 2004;203(1-3):69-76

3.  Chan TS, Moridani M, Siraki A, Scobie H, Beard K, Eghbal MA, Galati G, O'Brien PJ. Hydrogen peroxide supports hepatocyte P450 catalysed xenobiotic/drug metabolic activation to form cytotoxic reactive intermediates. Adv. Exp. Med. Biol., 2001, 500:233-236.

4.  Eghbal , Moridani, Pennefather, O'Brien. Preventing acrolein and -haloacetaldehyde induced cytotoxicity with garlic and onion reactive mercaptans. Drug Metabol. Rev., 2001, 33(supplement 1): 235 [Abstract]

  Congress, Lectures

o Eghbal MA, Pennefather PS, O'Brien PJ. H2S cytotoxicity mechanism involves reactive oxygen species formation and mitochondrial Toxicity. 9th Iranian Seminar of Pharmaceutical Sciences, Tabriz, Iran August 2004.

o Mohammad A. Eghbal, Shahrzad Tafazoli, Peter Pennefather and Peter J. O’Brien. Peroxidase catalysed formation of cytotoxic prooxidant phenothiazine free radicals at physiological pH. 9th Iranian Seminar of Pharmaceutical Sciences, Tabriz, Iran August 2004.

o  Eghbal, Moridani, Pennefather, O'Brien. Preventing acrolein and a-haloacetaldehyde induced cytotoxicity with garlic and onion reactive mercaptans. 6th ISSX Meeting, Munich, Germany, 2001.

o Eghbal M.A, Moridani M.Y., Pennefather PS, and O’Brien P.J.  (November 2001) Preventing Acrolein and a-Haloacetaldehyde Induced Oxidative Stress with Garlic and Onion Reactive Sulfur Containing Compounds. 15th Iranian Congress of Physiology and Pharmacology. Shiraz, Iran.

o  Peter S. Pennefather, Eghbal, Moridani, O'Brien. Preventing aldehyde or metal induced oxidative stress with reactive sulfur compounds. The Society for Free Radical Research, Liverpool, UK, July 2000.

o   Chan TS., Galati G., Moridani M., Siraki A., Scobie H., Beard K., Eghbal MA., and O’Brien P.J..
Hydrogen peroxide supports hepatocyte p450 catalysed xenobiotic/drug metabolism to form cytotoxic reactive intermediates. The Sixth International Symposium on Biological Reactive Intermediates, PARIS, Université René Descartes, July 16-20, 2000 .

o  Mohammad A. Eghbal, Bin Wu, Peter S. Pennefather and Peter J. O’Brien. (March 2000) 39th Annual Meeting of the Society of Toxicology. Pliladelphia, Pensylvania, U.S.A.

o  Mohammad A. Eghbal, Peter S. Pennefather and Peter J. O’Brien. (June 2000). 43RD Annual meeting of Canadian Federation of Biological Sciences. Ottawa, Ontario, Canada.

o Mohammad A. Eghbal, Peter J. O’brien and Peter S. Pennefather. (October 1999). 29th Annual Meeting of Society for Neuroscience. Miami Beach, Florida, U.S.A.

o   Eghbal, M. A., Ehsanpoor, M. R., and Gandiha, A. (1991 November) Effects of Clindamycine on striated muscles.  3th Iranian congress of pharmaceutical sciences. Ahwaz, Iran.

o  Eghbal, M. A., and Gandiha, A. (1990, October)  Effects of Polyethylen Glycol on Neuro-muscular Junctions. 9th Iranian congress of physiology and pharmacology, Ahwaz, Iran.

Posted by   Farnam Norouzi